Ever Wondered Just How Long to Treat Infant UTIs with IV Therapy? New Study Takes
a Peek at This Issue
LewisFirst, MD, MA, Editor in Chief, Pediatrics
When an infant is hospitalized with a urinary tract infection (UTI), intravenous (IV)
therapy is usually initiated. But how long should you use IV before changing over
to a per oral (PO) antibiotic? To answer that question, Lewis de Los Angeles et al.
(10.1542/peds.2017-1021) share the results of a retrospective analysis of infants less than 60 days who were
diagnosed and admitted at 46 free-standing children’s hospitals from 2005-2015 to
see if readmissions occurred and whether those readmissions were associated with a
shorter duration of IV therapy. The authors analyzed data using trends in duration
of IV antibiotic usage from 2005 to 2015. The good news is that the proportion of
infants who got 4 or more days of IV antibiotics decreased from 50% to 19% from 2005
to 2015. In fact there was no correlation over the period studied between duration
of antibiotics and readmissions suggesting using a shorter course of IV antibiotics.
So how long do you treat an infant with a UTI with IV antibiotics? Do you go with
the IV flow for at least four or more days, or do you move from IV to PO in the shortest
time period possible—and at what cost? Will this article change how you practice?
We’d love to hear your take on this study relative to what you do in your own practice
by responding to this blog, posting a comment on our website, or sharing your thoughts
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